malignancy

Etymology

malignant + -cy or malign + -ancy

noun

1. The state of being malignant or diseased.
2. A malignant cancer; specifically, any neoplasm that is invasive or otherwise not benign.
3. That which is malign; evil, depravity, malevolence.
   A cold wind swept down from it and set us shivering. Somewhere there, on that desolate plain, was lurking this fiendish man, hiding in a burrow like a wild beast, his heart full of malignancy against the whole race which had cast him out. 1902, Arthur Conan Doyle, The Hound of the Baskervilles