psychosis

Etymology

From psych- + -osis or from Ancient Greek ψύχωσις (psúkhōsis, “animation, principle of life”).

noun

1. (psychology) A severe mental disorder, sometimes with physical damage to the brain, marked by a deranged personality and a distorted view of reality.
   Manganism has been known about since the 19th century, when miners exposed to ores containing manganese[…]began to totter, slur their speech and behave like someone inebriated. The poisoning was irreversible, and soon ended in psychosis and death. 2014-04-21, “Subtle effects”, in The Economist, volume 411, number 8884